Specification-wise, AMD EPYC 4005 "Grado" series is pretty much the same as the Ryzen 9000 series desktop CPUs, featuring two 4nm Zen 5 CCDs paired up with a 6nm I/O. This time around it comes with support for ECC memory with DDR5-5600 support, and supports up to 192GB of ECC DDR5 memory in a dual-channel interface. It also comes with a 28-lane PCIe Gen 5, as well as AMD's own Secure Processor (ASP), TrustZone, hardware-accelerated encryption, memory encryption, TPM 2.0, and TSME. It also gets AMD RAIDXpert2 for Server, a software RAID solution.

The AMD EPYC 4005 "Grado" series features six SKUs, ranging from a 6-core/12-thread SKU, all the way to a 16-core/32-thread one. The flagship is the EPYC 4565P, a 16-core/32-thread SKU with 64MB of L3 cache (32MB per CCD), a 170W TDP, and a base frequency of 4.3GHz (5.7GHz boost). There is also a lower TDP 16-core/32-thread SKU, the EPCY 4545P, which has a lower 3.0GHz (5.4GHz boost) clock and 65W TDP.

The rest of the lineup includes the EPYC 4465P, a 12-core/24-thread SKU with 3.4GHz base (5.4GHz boost) clock and 65W TDP, the EPCY 4345P, an 8-core/16-thread SKU that comes with a single CCD so has 32MB of L3 cache, 3.8GHz base (5.5GHz boost) clcok and the same 65W TDP, and the EPCY 4245P, a 6-core/12-thread SKU with 32MB of L3 cache, 3.9GHz base (5.4GHz boost) clock and same 65W TDP.

AMD has listed several partners including Lenovo, MSI, Supermicro, ASRock, Gigabyte, and others as its partners.